Just finished (on the flight home from a business trip) DBII (Kra'an) with the single character wizard Mordor in 120 game days. I believe you can play the game through and win with any single character except Tesser (Trog) because of his light characteristic (keeps you from the ressurecting Timu).
I have already reported this next "issue": be aware that the game reduces max hits to 999 if they go over 1000 when you use an item that affects hits. It does the same with spell points if you use an item that affects spell points (and have more than 1000 max spell points). It also reduces actual hit points to max if you have more than your max and rest.
Two more unreported (minor) issues:
If you play with the lone thief, you still get the message you feel lighter at the trap(s) that steal stuff from your party even though he doesn't lose anything from inventory.
If you have a lone thief, the burgler can steal money from the party, even though it's not supposed to be possible to steal from a thief.
Craig